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Changes Implementing Nucleotide and/or Amino Acid Sequence Listings

The Patent and Trademark Office (PTO) is proposing to amend the rules for submitting nucleic acid or amino acid sequences in computer readable form (CRF) for patent applications to simplify the requirements of the rules, to rearrange portions of the rules for better understanding and to establish consistent rules to permit a single internationally acceptable computer readable form. The Sequence Listing will be presented in an international, language neutral format using numeric identifiers rather than the current subject headings and the paper Sequence Listing will be a separately numbered section of the patent application. Sequences which contain fewer than four (4) specifically identified nucleotides or amino acids will no longer be required to be submitted in computer readable form.

Task
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Patent or trademark
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Legacy system
—
Current entry point
www.federalregister.gov/documents/1996/10/04/96-25074/changes-implementing-nucleotide-andor-amino-acid-sequence-listings (permanent link in the Federal Register, verified 2026-09-30)
Legacy system and where it moved
No legacy system name mention in title or summary )
Fee
No fee mention in title or summary )
What you need (account or API key)
No account or key mention in title or summary )
Published
1996-10-04
Document type
Proposed Rule
Source
USPTO documents published in the Federal Register (Federal Register API)(retrieved 2026-10-06)

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